Nanophotonic and single-molecule biosensing at EPFL and TU/e

TheEuroTech Universities Allianceis a strategic partnership of leading European universities of science and technology:Technical University of Denmark (DTU)École Polytechnique Fédérale de Lausanne (EPFL)Institut Polytechnique de ParisTechnion - Israel Institute of TechnologyEindhoven University of Technology (TU/e)Technical University of Munich (TUM)The universities join forces to build a strong, sustainable, sovereign, and resilient Europe. The partners bring their excellence in research and education, their active engagement in vibrant eco-systems and service to society. Together, they join forces to accelerate their research in high-tech focus areas and advocate for change, through dedicated partners and a strong presence in Brussels.Based on the EuroTech values, the partners aspire to a new level of cooperation by bringing together their inclusive, diverse and sustainable campuses. The EuroTech Universities create a unique environment for international talents to lead a new generation of change agents in research, entrepreneurship, industry and society.

EuroTech Universities Alliance

Tackling global challenges together. A series of scientific online lectures by renowned researchers of EuroTech Universities

EuroTechTalks

The EuroTechTalks are a series of scientific online lectures by renowned researchers of EuroTech Universities. In the Alliance, we tackle global challenges together. This series highlights some outcomes of our scientific collaborations.

In this EuroTechTalk we will present nanophotonic and single-molecule biosensors that are being investigated at TU/e and EPFL, including research in the CONSENSE program, a European network that focusses on continuous biosensing technologies for personal health. Prof. Prins will present biosensors for the continuous monitoring of biomolecular targets, based on measuring Brownian motion of microparticles. The sensors employ particles on a surface, where the particles as well as the surface are provided with specific binder molecules. Motion traces are recorded of hundreds of particles, each revealing digital binding and unbinding events. The events are statistically analyzed and related to the biomarker concentration in solution. Large molecules (proteins, nucleic acids) and small molecules (oligonucleotides, metabolites) are being measured across a wide range of concentrations (picomolar to millimolar). Applications in industry and healthcare will be discussed, for early warning and closed-loop control based on real-time biochemical data. Prof. Altug will present nanophotonic technologies for optical biosensors, bioimaging and spectroscopy, based on nanofabrication, microfluidics, surface chemistry and data science. Nanoplasmonic and dielectric metasurfaces are developed for increased light-matter interaction in targeted spectral ranges including visible, near-infrared and mid-infrared. Nanofabrication methods allow high-throughput and low-cost manufacturing of nanophotonic structures and integration with microfluidics for automated sample handling. Data science tools with hyperspectral imaging and spectroscopy enable high device performances. Recent progress will be presented as well as prospects for applications.AboutThe EuroTechTalks are a series of scientific online lectures by renowned researchers of EuroTech Universities. In the Alliance, we tackle global challenges together. This series highlights some of our scientific collaborations.

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Nanophotonic and single-molecule biosensing at EPFL and TU/e

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Nanophotonic and single-molecule biosensing at EPFL and TU/e

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